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Prevalence of Asymptomatic Infection by Treponema pallidum in Pregnants of the Baixada Fluminense Region, Province of Rio de Janeiro, Brazil

Received: 18 April 2016     Accepted: 27 April 2016     Published: 14 May 2016
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Abstract

Syphilis is an infectious disease with worldwide distribution caused by Treponema pallidum, and has great clinical importance when the pathogenesis is in pregnant women. The congenital disease is the result of the infection by vertical transmission of the Treponema to the fetus and can be the cause of high morbidity of the concepts during intrauterine life. It can also cause serious problems during pregnancy such as expontaneous abortus, premature babies with low weight, stillbournes, neonatal mortality, and early or late complications in children who survive to the infection. The aim of this study is to investigate the prevalence of syphilis in pregnants in obstetrics clinics in the Baixada Fluminense region and advise the seropositives for appropriate treatment and evaluate the intervention, contributing to the eradicate to the maternal diseases and preventing the transmission of the Treponema to the concepts. During the years 2010 and 2011, venous blood samples were collected from 1183 asymptomatic adult pregnants accompanied by obstetricians to detect anti-T. pallidum. The serum obtained from the blood was frozen and stored at -20°C until the analysis by serologic reactions of Venereal Disease Research Laboratory (VDRL) and passive hemagglutination (TPHA). The results showed 28 cases were diagnosed with titers equal or superior to 1:16, suggestive of syphilitic disease, corresponding to the coefficient of prevalence of 2.37%. There were dominance of cases in pregnants in the etary group between 21 and 30 years old. There is asymptomatic infection among the examined pregnants of Baixada Fluminense region, with possible risk of vertical transmission of infection to their concepts.

Published in Science Journal of Public Health (Volume 4, Issue 3)
DOI 10.11648/j.sjph.20160403.20
Page(s) 224-228
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2016. Published by Science Publishing Group

Keywords

Syphilis, Abortus, Stillborn, Drug Treatment (Source: MeSH: MeSH NLM)

References
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[4] Tavares R, Gontijo EEL, Santos ES, Jubé JKB, Mazutti AR, Silva MG. Perfil de grávidas com sífilis, HIV+ ou hepatite B em Gurupi, Tocantins. Rev Saúde e Pesquisa 2014; 7(1): 35-45.
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[7] Macedo-Filho JV. Prevalência da sífilis em gestantes no estado de Goiás triadas pelo programa de proteção à gestante [master degree thesis]. Universidade de Brasília, 2008.
[8] Walker G, Walker D. Congenital syphilis. A continuing but neglected problem. Seminars in Fetal and Neonatal Medicine 2007; 12: 198-206.
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  • APA Style

    Ana Carolina Torres, Antonio Neres Norberg, Fabiano Guerra Sanches, Jose Tadeu Madeira-Oliveira, Alex Nagem Machado, et al. (2016). Prevalence of Asymptomatic Infection by Treponema pallidum in Pregnants of the Baixada Fluminense Region, Province of Rio de Janeiro, Brazil. Science Journal of Public Health, 4(3), 224-228. https://doi.org/10.11648/j.sjph.20160403.20

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    ACS Style

    Ana Carolina Torres; Antonio Neres Norberg; Fabiano Guerra Sanches; Jose Tadeu Madeira-Oliveira; Alex Nagem Machado, et al. Prevalence of Asymptomatic Infection by Treponema pallidum in Pregnants of the Baixada Fluminense Region, Province of Rio de Janeiro, Brazil. Sci. J. Public Health 2016, 4(3), 224-228. doi: 10.11648/j.sjph.20160403.20

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    AMA Style

    Ana Carolina Torres, Antonio Neres Norberg, Fabiano Guerra Sanches, Jose Tadeu Madeira-Oliveira, Alex Nagem Machado, et al. Prevalence of Asymptomatic Infection by Treponema pallidum in Pregnants of the Baixada Fluminense Region, Province of Rio de Janeiro, Brazil. Sci J Public Health. 2016;4(3):224-228. doi: 10.11648/j.sjph.20160403.20

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  • @article{10.11648/j.sjph.20160403.20,
      author = {Ana Carolina Torres and Antonio Neres Norberg and Fabiano Guerra Sanches and Jose Tadeu Madeira-Oliveira and Alex Nagem Machado and Paulo Cesar Ribeiro and Nicolau Maues Serra-Freire},
      title = {Prevalence of Asymptomatic Infection by Treponema pallidum in Pregnants of the Baixada Fluminense Region, Province of Rio de Janeiro, Brazil},
      journal = {Science Journal of Public Health},
      volume = {4},
      number = {3},
      pages = {224-228},
      doi = {10.11648/j.sjph.20160403.20},
      url = {https://doi.org/10.11648/j.sjph.20160403.20},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjph.20160403.20},
      abstract = {Syphilis is an infectious disease with worldwide distribution caused by Treponema pallidum, and has great clinical importance when the pathogenesis is in pregnant women. The congenital disease is the result of the infection by vertical transmission of the Treponema to the fetus and can be the cause of high morbidity of the concepts during intrauterine life. It can also cause serious problems during pregnancy such as expontaneous abortus, premature babies with low weight, stillbournes, neonatal mortality, and early or late complications in children who survive to the infection. The aim of this study is to investigate the prevalence of syphilis in pregnants in obstetrics clinics in the Baixada Fluminense region and advise the seropositives for appropriate treatment and evaluate the intervention, contributing to the  eradicate to the maternal diseases and preventing the transmission of the Treponema to the concepts. During the years 2010 and 2011, venous blood samples were collected from 1183 asymptomatic adult pregnants accompanied by obstetricians to detect anti-T. pallidum. The serum obtained from the blood was frozen and stored at -20°C until the analysis by serologic reactions of Venereal Disease Research Laboratory (VDRL) and passive hemagglutination (TPHA). The results showed 28 cases were diagnosed with titers equal or superior to 1:16, suggestive of syphilitic disease, corresponding to the coefficient of prevalence of 2.37%. There were dominance of cases in pregnants in the etary group between 21 and 30 years old. There is asymptomatic infection among the examined pregnants of Baixada Fluminense region, with possible risk of vertical transmission of infection to their concepts.},
     year = {2016}
    }
    

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  • TY  - JOUR
    T1  - Prevalence of Asymptomatic Infection by Treponema pallidum in Pregnants of the Baixada Fluminense Region, Province of Rio de Janeiro, Brazil
    AU  - Ana Carolina Torres
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    AU  - Paulo Cesar Ribeiro
    AU  - Nicolau Maues Serra-Freire
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    JO  - Science Journal of Public Health
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    PB  - Science Publishing Group
    SN  - 2328-7950
    UR  - https://doi.org/10.11648/j.sjph.20160403.20
    AB  - Syphilis is an infectious disease with worldwide distribution caused by Treponema pallidum, and has great clinical importance when the pathogenesis is in pregnant women. The congenital disease is the result of the infection by vertical transmission of the Treponema to the fetus and can be the cause of high morbidity of the concepts during intrauterine life. It can also cause serious problems during pregnancy such as expontaneous abortus, premature babies with low weight, stillbournes, neonatal mortality, and early or late complications in children who survive to the infection. The aim of this study is to investigate the prevalence of syphilis in pregnants in obstetrics clinics in the Baixada Fluminense region and advise the seropositives for appropriate treatment and evaluate the intervention, contributing to the  eradicate to the maternal diseases and preventing the transmission of the Treponema to the concepts. During the years 2010 and 2011, venous blood samples were collected from 1183 asymptomatic adult pregnants accompanied by obstetricians to detect anti-T. pallidum. The serum obtained from the blood was frozen and stored at -20°C until the analysis by serologic reactions of Venereal Disease Research Laboratory (VDRL) and passive hemagglutination (TPHA). The results showed 28 cases were diagnosed with titers equal or superior to 1:16, suggestive of syphilitic disease, corresponding to the coefficient of prevalence of 2.37%. There were dominance of cases in pregnants in the etary group between 21 and 30 years old. There is asymptomatic infection among the examined pregnants of Baixada Fluminense region, with possible risk of vertical transmission of infection to their concepts.
    VL  - 4
    IS  - 3
    ER  - 

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Author Information
  • Department of Pathology, Igua?u University – UNIG, Rio de Janeiro, Brazil

  • Department of Pathology, Souza Marques Medicine School – FTESM, Rio de Janeiro, Brazil

  • Department of Pathology, Igua?u University – UNIG, Rio de Janeiro, Brazil

  • Department of Pathology, UNIABEU University Center, Rio de Janeiro, Brazil

  • Department of Public Health, Medicine School of Manhua?u - FACIG, Manhua?u, Brazil

  • Department of Pathology, Igua?u University – UNIG, Rio de Janeiro, Brazil

  • Department of Public Health, Oswaldo Cruz Institute – IOC/FIOCRUZ, Rio de Janeiro, Brazil

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